Sort by Popularity - Most Popular Movies and TV Shows tagged with keyword "science-experiment"
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1. Spider-Man (2002)
PG-13 | 121 min | Action, Adventure, Sci-Fi
After being bitten by a genetically-modified spider, a shy teenager gains spider-like abilities that he uses to fight injustice as a masked superhero and face a vengeful enemy.
Director: Sam Raimi | Stars: Tobey Maguire, Kirsten Dunst, Willem Dafoe, James Franco
Votes: 879,999 | Gross: $403.71M
2. The Mist (2007)
R | 126 min | Horror, Sci-Fi, Thriller
A freak storm unleashes a species of bloodthirsty creatures on a small town, where a small band of citizens hole up in a supermarket and fight for their lives.
Director: Frank Darabont | Stars: Thomas Jane, Marcia Gay Harden, Laurie Holden, Andre Braugher
Votes: 340,505 | Gross: $25.59M
3. The Amazing Spider-Man (2012)
PG-13 | 136 min | Action, Adventure, Sci-Fi
After Peter Parker is bitten by a genetically altered spider, he gains newfound, spider-like powers and ventures out to save the city from the machinations of a mysterious reptilian foe.
Director: Marc Webb | Stars: Andrew Garfield, Emma Stone, Rhys Ifans, Irrfan Khan
Votes: 702,478 | Gross: $262.03M
4. Eureka (2006–2012)
TV-14 | 60 min | Adventure, Comedy, Drama
A U.S. Marshal becomes the sheriff of Eureka, a remote, cozy little Northwestern town where the best minds in the US have secretly been tucked away to build futuristic inventions for the government which often go disastrously wrong.
Stars: Colin Ferguson, Salli Richardson-Whitfield, Erica Cerra, Neil Grayston
Votes: 58,287
5. The Rocky Horror Picture Show (1975)
R | 100 min | Comedy, Horror, Musical
A newly-engaged couple have a breakdown in an isolated area and must seek shelter at the bizarre residence of Dr. Frank-n-Furter.
Director: Jim Sharman | Stars: Tim Curry, Susan Sarandon, Barry Bostwick, Richard O'Brien
Votes: 166,964 | Gross: $139.88M
6. Weird Science (1985)
PG-13 | 94 min | Comedy, Romance, Sci-Fi
Two high-school nerds use a computer program to literally create the perfect woman, who promptly turns their lives upside-down.
Director: John Hughes | Stars: Anthony Michael Hall, Ilan Mitchell-Smith, Kelly LeBrock, Bill Paxton
Votes: 97,455 | Gross: $23.83M
7. Quantum Leap (1989–1993)
TV-PG | 60 min | Action, Adventure, Drama
During an experiment into time travel, a scientist finds himself trapped in the past, "leaping" into the lives of different people, sorting out their problems and changing history in hopes of getting back to his own life in the present.
Stars: Scott Bakula, Dean Stockwell, Deborah Pratt, Dennis Wolfberg
Votes: 36,477
8. Source Code (2011)
PG-13 | 93 min | Action, Drama, Mystery
A soldier wakes up in someone else's body and discovers he's part of an experimental government program to find the bomber of a commuter train within 8 minutes.
Director: Duncan Jones | Stars: Jake Gyllenhaal, Michelle Monaghan, Vera Farmiga, Jeffrey Wright
Votes: 549,883 | Gross: $54.71M
9. Morbius (2022)
PG-13 | 104 min | Action, Adventure, Horror
Biochemist Michael Morbius tries to cure himself of a rare blood disease, but he inadvertently infects himself with a form of vampirism instead.
Director: Daniel Espinosa | Stars: Jared Leto, Matt Smith, Adria Arjona, Jared Harris
Votes: 153,464 | Gross: $73.87M
10. Twins (1988)
PG | 107 min | Comedy, Crime
A physically perfect but innocent man goes in search of his long-lost twin brother, who is short, a womanizer, and small-time crook.
Director: Ivan Reitman | Stars: Arnold Schwarzenegger, Danny DeVito, Kelly Preston, Chloe Webb
Votes: 137,303 | Gross: $111.94M
11. Splice (2009)
R | 104 min | Horror, Sci-Fi
Genetic engineers Clive Nicoli and Elsa Kast hope to achieve fame by successfully splicing together the DNA of different animals to create new hybrid animals for medical use.
Director: Vincenzo Natali | Stars: Adrien Brody, Sarah Polley, Delphine Chanéac, Brandon McGibbon
Votes: 101,790 | Gross: $17.00M
12. They Cloned Tyrone (2023)
R | 122 min | Comedy, Mystery, Sci-Fi
A series of eerie events thrusts an unlikely trio onto the trail of a nefarious government conspiracy in this pulpy mystery caper.
Director: Juel Taylor | Stars: John Boyega, Jamie Foxx, Teyonah Parris, Kiefer Sutherland
Votes: 40,513
13. Flatliners (1990)
R | 115 min | Drama, Horror, Sci-Fi
Five medical students experiment with "near death" experiences, until the dark consequences of past tragedies begin to jeopardize their lives.
Director: Joel Schumacher | Stars: Kiefer Sutherland, Kevin Bacon, Julia Roberts, William Baldwin
Votes: 93,461 | Gross: $61.49M
14. Spiderhead (2022)
R | 106 min | Action, Crime, Drama
In the near future, convicts are offered the chance to volunteer as medical subjects to shorten their sentence. One such subject for a new drug capable of generating feelings of love begins questioning the reality of his emotions.
Director: Joseph Kosinski | Stars: Chris Hemsworth, Miles Teller, Jurnee Smollett, Mark Paguio
Votes: 66,439
15. Lost in Space (1998)
PG-13 | 130 min | Action, Adventure, Family
The Robinson family was going into space to fight for a chance for humanity. Now they are fighting to live long enough to find a way home.
Director: Stephen Hopkins | Stars: Gary Oldman, William Hurt, Matt LeBlanc, Mimi Rogers
Votes: 74,872 | Gross: $69.12M
16. Firestarter (2022)
R | 94 min | Drama, Horror, Sci-Fi
A young girl tries to understand how she mysteriously gained the power to set things on fire with her mind.
Director: Keith Thomas | Stars: Zac Efron, Ryan Kiera Armstrong, Sydney Lemmon, Michael Greyeyes
Votes: 22,124
17. The Aeronauts (2019)
PG-13 | 100 min | Action, Adventure, Drama
A balloon pilot and a scientist find themselves in a fight for survival while attempting to make discoveries in a gas balloon in the 1860s.
Director: Tom Harper | Stars: Felicity Jones, Eddie Redmayne, Himesh Patel, Vincent Perez
Votes: 37,416
18. Frankenstein (1931)
Passed | 70 min | Drama, Horror, Sci-Fi
Dr Henry Frankenstein is obsessed with assembling a living being from parts of several exhumed corpses.
Director: James Whale | Stars: Colin Clive, Mae Clarke, Boris Karloff, John Boles
Votes: 79,726
19. The City of Lost Children (1995)
R | 112 min | Adventure, Drama, Fantasy
A scientist in a surrealist society kidnaps children to steal their dreams, hoping that they slow his aging process.
Directors: Marc Caro, Jean-Pierre Jeunet | Stars: Ron Perlman, Daniel Emilfork, Judith Vittet, Dominique Pinon
Votes: 71,674 | Gross: $1.51M
20. Project Power (2020)
R | 113 min | Action, Crime, Sci-Fi
When a pill that gives its users unpredictable superpowers for five minutes hits the streets of New Orleans, a teenage dealer and a local cop must team with an ex-soldier to take down the group responsible for its creation.
Directors: Henry Joost, Ariel Schulman | Stars: Jamie Foxx, Joseph Gordon-Levitt, Dominique Fishback, Rodrigo Santoro
Votes: 97,757
21. Temple Grandin (2010 TV Movie)
TV-PG | 107 min | Biography, Drama
A biopic of Temple Grandin, an autistic woman who has become one of the top scientists in the humane livestock handling industry.
Director: Mick Jackson | Stars: Claire Danes, Julia Ormond, David Strathairn, Catherine O'Hara
Votes: 32,581
22. Replicas (2018)
PG-13 | 107 min | Action, Drama, Sci-Fi
A scientist becomes obsessed with bringing back his family members who died in a traffic accident.
Director: Jeffrey Nachmanoff | Stars: Keanu Reeves, Alice Eve, Thomas Middleditch, John Ortiz
Votes: 42,047 | Gross: $4.05M
23. Happy Death Day 2U (2019)
PG-13 | 100 min | Comedy, Horror, Mystery
Tree Gelbman discovers that dying over and over was surprisingly easier than the dangers that lie ahead.
Director: Christopher Landon | Stars: Jessica Rothe, Israel Broussard, Phi Vu, Suraj Sharma
Votes: 85,355 | Gross: $28.15M
24. Frankenweenie (2012)
PG | 87 min | Animation, Comedy, Drama
When a boy's beloved dog passes away suddenly, he attempts to bring the animal back to life through a powerful science experiment.
Director: Tim Burton | Stars: Winona Ryder, Catherine O'Hara, Martin Short, Martin Landau
Votes: 117,131 | Gross: $35.29M
25. Dreamscape (1984)
PG-13 | 99 min | Action, Adventure, Horror
A man who can enter and manipulate people's dreams is recruited by a government agency to help cure the President of the United States of his nightmares about nuclear war but stumbles upon an assassination plot.
Director: Joseph Ruben | Stars: Dennis Quaid, Max von Sydow, Christopher Plummer, Eddie Albert
Votes: 18,159 | Gross: $11.48M
26. Pokémon: The First Movie - Mewtwo Strikes Back (1998)
G | 96 min | Animation, Action, Adventure
Scientists genetically create a new Pokémon, Mewtwo, but the results are horrific and disastrous.
Director: Kunihiko Yuyama | Stars: Veronica Taylor, Rachael Lillis, Eric Stuart, Rica Matsumoto
Votes: 46,061 | Gross: $85.74M
27. Silent Rage (1982)
R | 103 min | Action, Crime, Horror
A sheriff tries to stop the killing spree of a silent maniacal murderer who, as the result of secret genetic experimentation by an unethical scientist, has the ability to self-heal.
Director: Michael Miller | Stars: Chuck Norris, Ron Silver, Steven Keats, Toni Kalem
Votes: 6,709 | Gross: $10.49M
28. Young Sherlock Holmes (1985)
PG-13 | 109 min | Adventure, Fantasy, Mystery
When assorted people start having inexplicable delusions that lead to their deaths, a teenage Sherlock Holmes decides to investigate.
Director: Barry Levinson | Stars: Nicholas Rowe, Alan Cox, Sophie Ward, Anthony Higgins
Votes: 23,408 | Gross: $19.74M
29. The Experiment (2010)
R | 96 min | Drama, Thriller
26 men are chosen to participate in the roles of guards and prisoners in a psychological study that ultimately spirals out of control.
Director: Paul T. Scheuring | Stars: Adrien Brody, Cam Gigandet, Forest Whitaker, Maggie Grace
Votes: 57,181
30. The Addams Family 2 (2021)
PG | 93 min | Animation, Adventure, Comedy
The Addams get tangled up in more wacky adventures and find themselves involved in hilarious run-ins with all sorts of unsuspecting characters. Sequel to the 2019 animated film, 'The Addams Family'.
Directors: Conrad Vernon, Greg Tiernan, Laura Brousseau, Kevin Pavlovic | Stars: Oscar Isaac, Charlize Theron, Chloë Grace Moretz, Javon 'Wanna' Walton
Votes: 15,587 | Gross: $56.49M
31. Harriet the Spy (1996)
PG | 100 min | Comedy, Drama, Family
Harriet M. Welsch is a spy. But when her friends find her secret notebook, the tables are turned on her. Can she win them back and still keep on going with the spy business?
Director: Bronwen Hughes | Stars: Michelle Trachtenberg, Rosie O'Donnell, Gregory Smith, Vanessa Chester
Votes: 11,063 | Gross: $26.54M
32. Watchers (1988)
R | 91 min | Action, Horror, Sci-Fi
A boy takes in a stray dog, later discovering that it is an ultra-intelligent runaway being stalked by a dangerous creature from the same genetic research lab.
Director: Jon Hess | Stars: Corey Haim, Michael Ironside, Christopher Cary, Graeme Campbell
Votes: 4,699 | Gross: $0.94M
33. Boltneck (2000)
Not Rated | 92 min | Comedy, Horror, Sci-Fi
A student receives a serial killer's brain in a transplant after being thrown into a pool with no water in it.
Directors: Mitch Marcus, John Blush | Stars: Matthew Lawrence, Justin Walker, Christine Lakin, Christian Payne
Votes: 846
34. Cutting Class (1989)
R | 91 min | Comedy, Crime, Horror
A murderer is loose in a high school in this 'whodunit' movie.
Director: Rospo Pallenberg | Stars: Donovan Leitch Jr., Jill Schoelen, Brad Pitt, Roddy McDowall
Votes: 5,913
35. The Last Mimzy (2007)
PG | 90 min | Action, Adventure, Drama
Two siblings begin to develop special talents after they find a mysterious box of toys. Soon the kids, their parents, and even their teacher are drawn into a strange new world and find a task ahead of them that is far more important than any of them could imagine!
Director: Robert Shaye | Stars: Joely Richardson, Rainn Wilson, Timothy Hutton, Chris O'Neil
Votes: 22,222 | Gross: $21.47M
36. Superbabies: Baby Geniuses 2 (2004)
PG | 88 min | Comedy, Family, Sci-Fi
A group of smart-talking toddlers find themselves at the center of a media mogul's experiment to crack the code to baby talk. The toddlers must race against time for the sake of babies everywhere.
Director: Bob Clark | Stars: Jon Voight, Scott Baio, Vanessa Angel, Skyler Shaye
Votes: 31,692 | Gross: $9.11M
37. Beakman's World (1992–1997)
TV-PG | 30 min | Comedy, Family
A wacky scientist and his companions answer viewer questions about science.
Stars: Paul Zaloom, Mark Ritts, Eliza Schneider, Alanna Ubach
Votes: 2,979
38. Eliminators (1986)
PG | 96 min | Action, Adventure, Fantasy
A former pilot rebels against his creator, teaming up with the scientist responsible for android technology, her pet robot Spot, a rough-and-tumble riverboat guide, and a martial arts warrior.
Director: Peter Manoogian | Stars: Andrew Prine, Denise Crosby, Patrick Reynolds, Conan Lee
Votes: 2,511 | Gross: $4.60M
39. Leprechaun 4: In Space (1996 Video)
R | 95 min | Comedy, Fantasy, Horror
Our deadly leprechaun is in space to woo a beautiful princess who is impressed with his gold and desires to separate him from it.
Director: Brian Trenchard-Smith | Stars: Warwick Davis, Brent Jasmer, Jessica Collins, Guy Siner
Votes: 8,720
40. Day 5 (2016–2017)
45 min | Adventure, Comedy, Drama
An unexplainable epidemic has swept across the globe affecting every human being. People are frantically searching for answers because if you fall asleep... You die. How long can people stay awake?
Stars: Jesse C. Boyd, Walker Satterwhite, Stephanie Drapeau, Davi Jay
Votes: 1,422
41. Monkey Business (1952)
Approved | 97 min | Comedy, Sci-Fi
A chemist finds his personal and professional life turned upside down when one of his chimpanzees finds the fountain of youth.
Director: Howard Hawks | Stars: Cary Grant, Ginger Rogers, Marilyn Monroe, Charles Coburn
Votes: 15,576
42. Retroactive (1997)
R | 91 min | Action, Crime, Drama
A psychiatrist makes multiple trips through time to save a woman that was murdered by her brutal husband.
Director: Louis Morneau | Stars: Jim Belushi, Kylie Travis, Shannon Whirry, Frank Whaley
Votes: 6,706
43. Pokémon: Mewtwo Strikes Back - Evolution (2019)
TV-Y7 | 98 min | Animation, Action, Family
After a scientific experiment leads to the creation of a clone of Mewtwo, he sets out to destroy the world. Ash and his friends then decide to thwart Mewtwo's evil plans.
Directors: Motonori Sakakibara, Tetsuo Yajima, Kunihiko Yuyama | Stars: Sarah Natochenny, Dan Green, Bill Rogers, Michele Knotz
Votes: 6,288
44. Anti Matter (2016)
109 min | Horror, Mystery, Sci-Fi
A scientist faces the question of what makes us whole and if there is a part of us that is not part of this physical world when she discovers how to travel through a worm hole.
Director: Keir Burrows | Stars: Yaiza Figueroa, Philippa Carson, Tom Barber-Duffy, Noah Maxwell Clarke
Votes: 6,129
45. Jinxed (2013 TV Movie)
G | 75 min | Comedy, Family
After a century-old curse of bad luck, a determined teen embarks on a journey to break her family's generational misfortune.
Director: Stephen Herek | Stars: Ciara Bravo, Jacob Bertrand, Elena Kampouris, Jack Griffo
Votes: 1,765
46. The Other Me (2000 TV Movie)
TV-G | 90 min | Comedy, Family, Sci-Fi
Will Browning accidentally creates a clone of himself when working on a science project.
Director: Manny Coto | Stars: Andrew Lawrence, Mark L. Taylor, Lori Hallier, Alison Pill
Votes: 2,325
47. After Last Season (2009)
PG-13 | 93 min | Drama, Sci-Fi, Thriller
Two neurology students create a telepathy experiment together to visualize a murderer, who recently knifed another student.
Director: Mark Region | Stars: Jason Kulas, Peggy McClellan, Scott Winters, Casey McDougal
Votes: 8,508
48. Vanishing Waves (II) (2012)
Unrated | 124 min | Romance, Sci-Fi, Thriller
A neuron-transfer scientist experiments with the thoughts of a comatose young woman.
Director: Kristina Buozyte | Stars: Marius Jampolskis, Jurga Jutaite, Rudolfas Jansonas, Vytautas Kaniusonis
Votes: 2,861
49. The Incredible 2-Headed Transplant (1971)
R | 88 min | Horror, Sci-Fi
Dr. Roger Girard, a mad scientist who dares to combine two heads onto one body, despite serious consequences.
Director: Anthony M. Lanza | Stars: Bruce Dern, Pat Priest, Casey Kasem, Albert Cole
Votes: 1,841 | Gross: $0.35M
50. Crime + Punishment in Suburbia (2000)
R | 100 min | Drama, Thriller
A darkly romantic story of murder and redemption, set against an eerily familiar American landscape.
Director: Rob Schmidt | Stars: Monica Keena, Ellen Barkin, Michael Ironside, Vincent Kartheiser
Votes: 3,512 | Gross: $0.03M