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Splice (2009)

R  |   |  Horror, Sci-Fi  |  4 June 2010 (USA)
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Ratings: 5.8/10 from 76,042 users   Metascore: 66/100
Reviews: 355 user | 364 critic | 35 from

Genetic engineers Clive Nicoli and Elsa Kast hope to achieve fame by successfully splicing together the DNA of different animals to create new hybrid animals for medical use.



(screenplay), (screenplay), 3 more credits »
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Complete credited cast:
Dren (as Delphine Chaneac)
Simona Maicanescu ...
Joan Chorot
William Barlow


Two young rebellious scientists are told by their employers to halt groundbreaking work that has seen them produce new creatures with medical benefits by splicing together multiple organisms' DNA. They decide to secretly continue their work, but this time splicing in human DNA. Written by Anonymous

Plot Summary | Plot Synopsis


She's Not Human ... Not Entirely. See more »


Horror | Sci-Fi

Motion Picture Rating (MPAA)

Rated R for disturbing elements including strong sexuality, nudity, sci-fi violence and language | See all certifications »

Parents Guide:




| |



Release Date:

4 June 2010 (USA)  »

Also Known As:

Hibrid  »

Filming Locations:


Box Office


$26,000,000 (estimated)

Opening Weekend:

$7,385,277 (USA) (4 June 2010)


£239,538 (UK) (30 July 2010)

Company Credits

Show detailed on  »

Technical Specs


Sound Mix:

| |


Aspect Ratio:

1.85 : 1
See  »

Did You Know?


Vincenzo Natali first got the idea for the film when he saw a picture of a mouse with a human ear growing on its back. See more »


When Elsa finds Clive and Dren in the barn, she stands in the wide-open door. In the next shot, from outside, Elsa throws the barn door open and runs out. See more »


CEO: No more monsters!
See more »

Crazy Credits

The cast credits and finally the title are scattered throughout the opening credits, instead of appearing consecutively. See more »


Hail Destroyer
Written and Performed by Cancer Bats
Courtesy of Distort Inc.
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Frequently Asked Questions

See more (Spoiler Alert!) »

User Reviews

Playing of God
9 April 2011 | by (Rio de Janeiro, Brazil) – See all my reviews

Clive Nicoli (Adrien Brody) and Elsa Kast (Sarah Polley) are scientists of the Newstead Pharmaceutics researching the splice of DNA from different animals to form new genetic beings and find medical benefits to mankind. They have just created the hybrid Ginger and Fred and now they intend to join together human DNA to alter the genetic structure of their experiment. When the senior management calls off their experiment, they decide to secretly proceed and they generate a life form with human characteristics. They call it Dren (Delphine Chaneac) and Elsa is very fond of their creation that grows up fast and showing intelligence. When the company shutdown their experiment, they bring Dren to Elsa's abandoned farm and the scientists raise Dren like a daughter. But when it reaches adulthood, the sex drive of Dren is activated and Clive and Elsa learn that they have a serious problem to resolve.

"Splice" is a dramatic sci-fi horror film with the story of two young unethical scientists that decide to play God. The plot is unoriginal but is attractive and engaging, specially because the trio formed by Sarah Polley, Adrian Brody and Delphine Chanéac. The childhood trauma of Elsa is absolutely out of the context and a diversion to the mainstream. The special effects and make-up are awesome, transforming the gorgeous French actress Delphine Chanéac in a creature with an exotic beauty. My vote is seven.

Title (Brazil): "Splice – A Nova Espécie" ("Splice – The New Specie")

27 of 38 people found this review helpful.  Was this review helpful to you?

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Elsa, one of the most insufferable characters ever written into a movie. genesis_omega5
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