Sort by Popularity - Most Popular Movies and TV Shows tagged with keywords "despair", "scientist"

1. 28 Days Later (2002)

R | 113 min | Drama, Horror, Sci-Fi

Four weeks after a mysterious, incurable virus spreads throughout the UK, a handful of survivors try to find sanctuary.

Director: Danny Boyle | Stars: Cillian Murphy, Naomie Harris, Christopher Eccleston, Alex Palmer

Votes: 446,651 | Gross: $45.06M

2. Tenet (2020)

PG-13 | 150 min | Action, Sci-Fi, Thriller

Armed with only the word "Tenet," and fighting for the survival of the entire world, CIA operative, The Protagonist, journeys through a twilight world of international espionage on a global mission that unfolds beyond real time.

Director: Christopher Nolan | Stars: John David Washington, Robert Pattinson, Elizabeth Debicki, Juhan Ulfsak

Votes: 593,961 | Gross: $58.46M

3. Independence Day (1996)

PG-13 | 145 min | Action, Adventure, Sci-Fi

The aliens are coming and their goal is to invade and destroy Earth. Fighting superior technology, mankind's best weapon is the will to survive.

Director: Roland Emmerich | Stars: Will Smith, Bill Pullman, Jeff Goldblum, Mary McDonnell

Votes: 606,422 | Gross: $306.17M

4. The NeverEnding Story (1984)

PG | 102 min | Adventure, Drama, Family

A troubled boy dives into a wondrous fantasy world through the pages of a mysterious book.

Director: Wolfgang Petersen | Stars: Noah Hathaway, Barret Oliver, Tami Stronach, Gerald McRaney

Votes: 157,201 | Gross: $20.16M

5. Life (I) (2017)

R | 104 min | Horror, Sci-Fi, Thriller

A team of scientists aboard the International Space Station discover a rapidly evolving life form that caused extinction on Mars and now threatens all life on Earth.

Director: Daniel Espinosa | Stars: Jake Gyllenhaal, Rebecca Ferguson, Ryan Reynolds, Hiroyuki Sanada

Votes: 254,349 | Gross: $30.23M

6. I Am Legend (2007)

PG-13 | 101 min | Action, Drama, Horror

Years after a plague kills most of humanity and transforms the rest into monsters, the sole survivor in New York City struggles valiantly to find a cure.

Director: Francis Lawrence | Stars: Will Smith, Alice Braga, Charlie Tahan, Salli Richardson-Whitfield

Votes: 815,791 | Gross: $256.39M

7. The Theory of Everything (2014)

PG-13 | 123 min | Biography, Drama, Romance

Stephen Hawking gets unprecedented success in the field of physics despite being diagnosed with motor neuron disease at the age of 21. He defeats awful odds as his first wife Jane aids him loyally.

Director: James Marsh | Stars: Eddie Redmayne, Felicity Jones, Tom Prior, Sophie Perry

Votes: 482,627 | Gross: $35.89M

8. Elfen Lied (2004)

TV-MA | 24 min | Animation, Action, Drama

Two university students come across a seemingly harmless girl named Lucy, unaware that she's actually a mutant serial killer with a split personality.

Stars: Sanae Kobayashi, Chihiro Suzuki, Mamiko Noto, Sam Saletta

Votes: 36,990

9. Day of the Dead (1985)

Not Rated | 101 min | Horror, Thriller

As the world is overrun by zombies, a group of scientists and military personnel sheltering in an underground bunker in Florida must decide on how they should deal with the undead horde.

Director: George A. Romero | Stars: Lori Cardille, Terry Alexander, Joseph Pilato, Jarlath Conroy

Votes: 74,485 | Gross: $5.80M

10. A Wrinkle in Time (2018)

PG | 109 min | Adventure, Drama, Family

After the disappearance of her scientist father, three peculiar beings send Meg, her brother, and her friend to space in order to find him.

Director: Ava DuVernay | Stars: Storm Reid, Oprah Winfrey, Reese Witherspoon, Mindy Kaling

Votes: 47,824 | Gross: $100.48M

11. The Fly (1958)

Not Rated | 94 min | Drama, Horror, Sci-Fi

A scientist has a horrific accident when he tries to use his newly invented teleportation device.

Director: Kurt Neumann | Stars: David Hedison, Patricia Owens, Vincent Price, Herbert Marshall

Votes: 25,692 | Gross: $3.00M

12. Lorenzo's Oil (1992)

PG-13 | 129 min | Biography, Drama

Lorenzo Odone, a Virginia 5-year-old, develops a degenerative nerve disease so rare that nobody is working on a cure, so his parents decide to immerse themselves in research and tackle the problem themselves.

Director: George Miller | Stars: Nick Nolte, Susan Sarandon, Peter Ustinov, Kathleen Wilhoite

Votes: 24,059 | Gross: $7.29M

13. The Invisible Man (1933)

TV-PG | 71 min | Horror, Sci-Fi

A scientist finds a way of becoming invisible, but in doing so, he becomes murderously insane.

Director: James Whale | Stars: Claude Rains, Gloria Stuart, William Harrigan, Henry Travers

Votes: 40,015

14. After Death (1989)

Unrated | 84 min | Action, Horror

A woman goes back to the island where her parents were killed. They had been working on a cure for cancer and accidentally raised the dead by angering a voodoo priest. With the woman is a ... See full summary »

Director: Claudio Fragasso | Stars: Jeff Stryker, Candice Daly, Massimo Vanni, Jim Gaines

Votes: 2,891

15. My House in Umbria (2003 TV Movie)

TV-14 | 103 min | Drama, Mystery, Romance

An unlikely group of people find solace and friendship after being thrown together in the wake of a terrorist attack.

Director: Richard Loncraine | Stars: Maggie Smith, Ronnie Barker, Chris Cooper, Benno Fürmann

Votes: 3,635

16. The Galapagos Affair: Satan Came to Eden (2013)

Not Rated | 120 min | Documentary, Biography, Crime

About a series of unsolved disappearances on the Galapagos Island of Floreana in the 1930s.

Directors: Daniel Geller, Dayna Goldfine | Stars: Cate Blanchett, Sebastian Koch, Thomas Kretschmann, Diane Kruger

Votes: 1,497 | Gross: $0.25M

17. Brynhildr in the Darkness (2014)

TV-MA | 22 min | Animation, Action, Drama

When he was a child, Murakami was infatuated with a girl he called Kuroneko. She insisted on knowing about aliens and having met them, but no one believed her, even young Murakami was skeptical.

Stars: Jamie Marchi, Blake Shepard, Ryôta Ôsaka, Risa Taneda

Votes: 1,120

18. Man Made Monster (1941)

Passed | 59 min | Drama, Horror, Romance

A mad scientist turns a man into an electrically-controlled monster to do his bidding.

Director: George Waggner | Stars: Lionel Atwill, Lon Chaney Jr., Anne Nagel, Frank Albertson

Votes: 1,882

19. The Monster and the Girl (1941)

Passed | 65 min | Crime, Drama, Horror

After a young woman is coerced into prostitution and her brother framed for murder by an organized crime syndicate, retribution in the form of an ape visits the mobsters.

Director: Stuart Heisler | Stars: Ellen Drew, Robert Paige, Paul Lukas, Joseph Calleia

Votes: 761

20. Jungle Jim (1948)

Passed | 71 min | Adventure, Family

Lady scientist, Hilary Parker is searching for a rare drug to help combat polio. Opportunist Bruce Edwards joins the quest but is actually after gold and buried treasure.

Director: William Berke | Stars: Johnny Weissmuller, Virginia Grey, George Reeves, Lita Baron

Votes: 812

21. Isola: Multiple Personality Girl (2000)

94 min | Drama, Horror, Mystery

When a woman, able to read the thoughts of others, comes to help survivors of the 1995 Kobe earthquake, she encounters a girl with Multiple Personality Disorder whose dangerous 13th personality, Isola, must be stopped.

Director: Toshiyuki Mizutani | Stars: Yoshino Kimura, Yû Kurosawa, Ken Ishiguro, Makiko Watanabe

Votes: 377

22. Night Unto Night (1949)

Approved | 84 min | Drama, Romance

A scientist afflicted with the incurable illness epilepsy, meets a beautiful woman haunted by the voice of her dead husband.

Director: Don Siegel | Stars: Ronald Reagan, Viveca Lindfors, Broderick Crawford, Rosemary DeCamp

Votes: 521

23. The Directive (2019)

113 min | Action, Comedy, Sci-Fi

One year after a catastrophic pandemic wipes out most of humanity, a lone survivor embarks on a journey to find Safe Zone 57 with the help of a broken robot.

Director: Alexander Raye Pimentel | Stars: Nicholas Winand, Thomas Betthauser, Scott Thompson, Blaiden D. Cordle

Votes: 1,317

24. Cumulus 9 (1992 Video)

93 min | Action, Adventure, Fantasy

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Director: Aaron Michael Lacey | Stars: Aaron Michael Lacey, Reza Fayyazi, Annemette Andersen, Langford King Jordan

Votes: 69

25. Space: 1999 (1975–1977)
Episode: Missing Link (1976)

TV-14 | 60 min | Adventure, Drama, Sci-Fi

After Commander Koening's Eagle crashes on the planet Zenno, his soul is captured and scrutinized by a resident alien, due to the fact that we humans appear to be their missing link.

Director: Ray Austin | Stars: Martin Landau, Barbara Bain, Barry Morse, Joanna Dunham

Votes: 329

26. Nova (1974– )
Episode: Dogs Decoded (2010)

TV-G | 54 min | Documentary

Nova examines the special relationship that exists between human beings and dogs.

Star: Lance Lewman

Votes: 157

27. The Matt Walsh Show (2018– )
Trump Is Indicted. The Justice System Is a Sham. (2023 Podcast Episode)

News, Talk-Show

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Star: Matt Walsh