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Lorenzo's Oil (1992)

PG-13 | | Drama | 29 January 1993 (USA)
A boy develops a disease so rare that nobody is working on a cure, so his father decides to learn all about it and tackle the problem himself.



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Nominated for 2 Oscars. Another 5 nominations. See more awards »



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Cast overview, first billed only:
Deirdre Murphy
Doctor Judalon
Wendy Gimble
Ellard Muscatine
Loretta Muscatine
Mary Wakio ...
Comorian Teacher
Don Suddaby ...
Colin Ward ...
Jake Gimble
Nurse Ruth (as La Tanya Richardson)
Nurse Nancy Jo
William Cameron ...


Until about the age of 7, Lorenzo Odone was a normal child. After then, strange things began to happen to him: he would have blackouts, memory lapses, and other strange mental phemonenons. He is eventually diagnosed as suffering from ALD: an extremely rare incurable degenerative brain disorder. Frustrated at the failings of doctors and medicine in this area, the Odones begin to educate themselves in the hope of discovering something which can halt the progress of the disease. Written by Murray Chapman <muzzle@cs.uq.oz.au>

Plot Summary | Add Synopsis

Plot Keywords:

disease | ald | brain | hope | medicine | See All (217) »


Some people make their own miracles.



Motion Picture Rating (MPAA)

Rated PG-13 for a child's life threatening ordeal | See all certifications »

Parents Guide:






Release Date:

29 January 1993 (USA)  »

Also Known As:

Un milagro para Lorenzo  »

Box Office


$30,000,000 (estimated)


$7,286,388 (USA)

Company Credits

Show detailed on  »

Technical Specs


Sound Mix:



Aspect Ratio:

1.85 : 1
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Did You Know?


Michelle Pfeiffer was originally cast as Michaela Odone but dropped out in order to play Catwoman in Batman Returns (1992) a role that Susan Sarandon also expressed interest in. The script for "Lorenzo's Oil" was given to Sarandon but she steadfastly refused to read it until she knew that Pfeiffer was no longer participating in the film. See more »


Augusto Odone: Dr. Nikolias, what about the other boys, what results are you seeing in them?
Professor Nikolias: As with Lorenzo it's too early to tell. We need this study to run for the full six months.
Augusto Odone: And that would tell you what is obvious right now? That avoiding apple skins and pizza has no effect on this brutal disease?
See more »

Crazy Credits

During the credits pictures of children are shown, which were cured by "Lorenzo's Oil". See more »


Featured in How Art Made the World (2005) See more »

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User Reviews

Gripping and moving drama
20 June 2000 | by (Miami, Florida) – See all my reviews

"Lorenzo's Oil" is a movie about the triumph of human spirit and dogged determination. This movie is based on the true story of Michaela and Agusto Odone, whose child Lorenzo was diagnosed with adrenoleukodystrophy (ALD), a degenerative nerve disorder that afflicts only little boys and is always fatal. Michaela and Agusto are determined to find a cure or treatment for this baffling disease while their son slowly and painfully deteriorates. That is the basic premise for the movie, but it is about much more than that.

Michaela and Agusto love their son with unwavering selflessness, and are willing to do anything in their power to save him. This movie is a gripping, touching drama that pulls you in and engulfs you, as finding a cure engulfs the Odones. By the end of the film you will feel a mix of emotions. This movie will give you a newfound respect for the mental and emotional power humans possess.

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