Sort by Popularity - Most Popular Movies and TV Shows tagged with keyword "degenerative-disease"

1. The Notebook (2004)

PG-13 | 123 min | Drama, Romance

An elderly man reads to a woman with dementia the story of two young lovers whose romance is threatened by the difference in their respective social classes.

Director: Nick Cassavetes | Stars: Gena Rowlands, James Garner, Rachel McAdams, Ryan Gosling

Votes: 621,497 | Gross: $81.00M

2. Love & Other Drugs (2010)

R | 112 min | Comedy, Drama, Romance

In 1990s Pittsburgh, a medicine peddler starts a relationship with a young woman suffering from Parkinson's disease.

Director: Edward Zwick | Stars: Jake Gyllenhaal, Anne Hathaway, Judy Greer, Oliver Platt

Votes: 224,689 | Gross: $32.37M

3. Night Swim (2024)

PG-13 | 98 min | Horror, Thriller

A family moves into a new home, unaware that a dark secret from the house's past will unleash a malevolent force in the backyard pool.

Director: Bryce McGuire | Stars: Wyatt Russell, Kerry Condon, Amélie Hoeferle, Gavin Warren

Votes: 17,668

4. The Theory of Everything (2014)

PG-13 | 123 min | Biography, Drama, Romance

Stephen Hawking gets unprecedented success in the field of physics despite being diagnosed with motor neuron disease at the age of 21. He defeats awful odds as his first wife Jane aids him loyally.

Director: James Marsh | Stars: Eddie Redmayne, Felicity Jones, Tom Prior, Sophie Perry

Votes: 482,688 | Gross: $35.89M

5. Boss (2011–2012)

TV-MA | 60 min | Crime, Drama

Mayor Tom Kane, diagnosed with a dementia disorder, struggles to keep his grip on power in Chicago.

Stars: Kelsey Grammer, Connie Nielsen, Hannah Ware, Jeff Hephner

Votes: 18,362

6. The Taking of Deborah Logan (2014)

R | 90 min | Horror, Mystery, Thriller

An elderly woman battling Alzheimer's disease agrees to let a film crew document her condition, but what they discover is something far more sinister going on.

Director: Adam Robitel | Stars: Jill Larson, Anne Ramsay, Michelle Ang, Brett Gentile

Votes: 40,351

7. Still Alice (2014)

PG-13 | 101 min | Drama

A linguistics professor and her family find their bonds tested when she is diagnosed with Alzheimer's Disease.

Directors: Richard Glatzer, Wash Westmoreland | Stars: Julianne Moore, Alec Baldwin, Kristen Stewart, Kate Bosworth

Votes: 143,619 | Gross: $18.75M

8. One Fine Morning (2022)

R | 112 min | Drama, Romance

With a father suffering from neurodegenerative disease, a young woman lives with her eight-year-old daughter. While struggling to secure a decent nursing home, she runs into an unavailable friend with whom she embarks on an affair.

Director: Mia Hansen-Løve | Stars: Léa Seydoux, Pascal Greggory, Melvil Poupaud, Nicole Garcia

Votes: 6,975

9. Still: A Michael J. Fox Movie (II) (2023)

R | 95 min | Documentary, Biography

Follows the life of beloved actor and advocate Michael J. Fox, exploring his personal and professional triumphs and travails, and what happens when an incurable optimist confronts an incurable disease.

Director: Davis Guggenheim | Stars: Michael J. Fox, Davis Guggenheim, Tracy Pollan, Sam Fox

Votes: 15,308

10. The Sea Inside (I) (2004)

PG-13 | 126 min | Biography, Drama

The factual story of Spaniard Ramon Sampedro, who fought a 28-year campaign in favor of euthanasia and his own right to die.

Director: Alejandro Amenábar | Stars: Javier Bardem, Belén Rueda, Lola Dueñas, Mabel Rivera

Votes: 85,299 | Gross: $2.09M

11. Late Night (2019)

R | 102 min | Comedy, Drama

A late night talk show host suspects that she may soon lose her long-running show.

Director: Nisha Ganatra | Stars: Emma Thompson, Mindy Kaling, John Lithgow, Hugh Dancy

Votes: 40,873 | Gross: $15.50M

12. You're Not You (2014)

R | 102 min | Drama

A drama centered on a classical pianist who has been diagnosed with ALS and the brash college student who becomes her caregiver.

Director: George C. Wolfe | Stars: Hilary Swank, Emmy Rossum, Josh Duhamel, Stephanie Beatriz

Votes: 26,854

13. Remember: War of the Son (2015–2016)

60 min | Drama, Thriller

Jin-Woo is a young man with the condition of Hyperthymesia, which allows him to remember everything in details. In order to prove that his father is innocence, he becomes a lawyer and make a team to solve different cases using his memory.

Stars: Yoo Seung-ho, Park Min-Young, Min Nam-koong, Park Sung-woong

Votes: 1,219

14. Ludwig (1973)

R | 238 min | Biography, Drama, History

The reign of the tormented Ludwig, king of Bavaria, from 1864 to 1886.

Director: Luchino Visconti | Stars: Helmut Berger, Romy Schneider, Trevor Howard, Silvana Mangano

Votes: 6,009

15. Frankenstein: The True Story (1973 TV Movie)

Not Rated | 185 min | Drama, Horror, Sci-Fi

When the brilliant but unorthodox scientist Dr. Victor Frankenstein rejects the artificial man that he has created, the Creature escapes and later swears revenge.

Director: Jack Smight | Stars: James Mason, Leonard Whiting, David McCallum, Jane Seymour

Votes: 1,967

16. A Moment to Remember (2004)

PG-13 | 117 min | Drama, Romance

A young couple's enduring love is tested when 27-year-old Su-jin is diagnosed with a rare form of Alzheimer's disease.

Directors: Park Kyung-Jin, John H. Lee, Kim Tae-Won | Stars: Jung Woo-sung, Son Ye-jin, Jong-hak Baek, Lee Seon-jin

Votes: 25,600

17. Big Nothing (2006)

R | 86 min | Comedy, Crime, Thriller

A frustrated, unemployed professor joins forces with a scammer and a friend of his in a blackmailing scheme.

Director: Jean-Baptiste Andrea | Stars: David Schwimmer, Simon Pegg, Alice Eve, Jon Polito

Votes: 31,850

18. Spider Baby or, the Maddest Story Ever Told (1967)

Not Rated | 81 min | Comedy, Horror

A caretaker devotes himself to three demented siblings after their father's death.

Director: Jack Hill | Stars: Lon Chaney Jr., Carol Ohmart, Quinn K. Redeker, Beverly Washburn

Votes: 7,821

19. What Makes a Family (2001 TV Movie)

TV-14 | 91 min | Drama

When an artificially-inseminated woman dies, her partner must fight to regain custody of their child.

Director: Maggie Greenwald | Stars: Brooke Shields, Cherry Jones, Anne Meara, Al Waxman

Votes: 817

20. The Fall of the House of Usher (1950)

TV-14 | 70 min | Horror

1950. Horror. A traveller arrives at Usher mansion to visit his friend Roderick (Kaye Tendeter) and discovers that Roderick and his sister (Gwen Watford) have been inflicted with a strange disease.

Director: Ivan Barnett | Stars: Gwen Watford, Kaye Tendeter, Irving Steen, Vernon Charles

Votes: 571

21. Romanovy: Ventsenosnaya semya (2000)

140 min | Biography, Drama, History

The story of the last year and a half of Tsar Nicholas II and his family from the February Revolution of 1917 to their execution in July 1918.

Director: Gleb Panfilov | Stars: Aleksandr Galibin, Lynda Bellingham, Vladimir Grachyov, Yuliya Novikova

Votes: 360

22. Lourdes (2019)

95 min | Documentary

The rock of the Grotto of Lourdes is caressed by tens of millions of people who left there the imprint of their dreams, their expectations, their hopes and their sentences. In Lourdes converge all the fragilities.

Directors: Thierry Demaizière, Alban Teurlai

Votes: 288

23. Dying to Have Known (2006)

Not Rated | 80 min | Documentary

Master filmmaker Steve Kroschel, intrigued by a stunning statement from his last documentary, sets out to find hard evidence of the effectiveness of the Gerson Therapy, a long-suppressed ... See full summary »

Director: Steve Kroschel | Stars: Stephen Barret, T. Colin Campbell, Carolyn Dean, Dean Edell

Votes: 223

24. A Risk Worth Taking (2008 TV Movie)

90 min | Drama

A woman caring for her terminally ill husband who she loves dearly develops feelings for his best friend who has come to assist her with their business. Will she resist the temptation?

Director: Paul Seed | Stars: Muriel Baumeister, Rachael Reilly, James Wilby, Tim Dutton

Votes: 85

25. Have You Heard About Greg? (2021)

PG-13 | 87 min | Documentary

A unique cinematic journey that puts a human face on the most terrifying disease of Alzheimer's and other forms of dementia, shining a light on issues that affect 50% of Americans over the age of 55.

Director: Steve Ecclesine | Stars: Greg O'Brien, Lisa Genova, Doug Scalise, Rudolph Tanzi

Votes: 10

26. Ein Sommer in Masuren (2015 TV Movie)

89 min | Comedy

A German woman from Franckfurt has been fired from her job in the bank when she receives news about her father's death. After that, she's informed she's the heiress of some land located in ... See full summary »

Director: Karola Meeder | Stars: Christina Große, Stefan Murr, Irene Rindje, Witold Debicki

Votes: 69

27. Through the Needle (2009)

19 min | Short, Drama

A passionate, yet desperate man fulfills his dream in a forbidden encounter with a young girl who herself was forced to grow up too quickly.

Director: Benjamin Capps | Stars: Steven Saines, Kate Liz, Sara Sylvan

Votes: 15

28. Screen One (1985–2002)
Episode: Wide-Eyed and Legless (1993)

PG-13 | 102 min | Comedy, Crime, Drama

The movie chronicles the struggles of Deric and Diana Longden, a happily married couple who try to cope with Diana's inexplicable degenerative disease which causes occasional paralysis of ... See full summary »

Director: Richard Loncraine | Stars: Julie Walters, Jim Broadbent, Thora Hird, Sian Thomas

Votes: 230 | Gross: $0.21M

29. Baywatch (1989–2001)
Episode: Blindside (1993)

TV-PG | 42 min | Action, Adventure, Crime

Former Baywatch lifeguard, John D. Cort, returns to Baywatch wanting to becomes a lifeguard again and tries to rekindle the flame with his former girlfriend C.J. But after a series of ... See full summary »

Director: Douglas Schwartz | Stars: David Hasselhoff, Nicole Eggert, David Charvet, Pamela Anderson

Votes: 170

30. PSI Factor: Chronicles of the Paranormal (1996–2000)
Episode: 883 (1999)

TV-14 | 45 min | Drama, Fantasy, Mystery

Matt finds a disfigured mute with number 883 embedded on his arm. His toxic blood infects Matt and slowly starts killing him. Matt's only chance for survival is the secretive female doctor behind the genetic experiment that created 883.

Director: Ron Oliver | Stars: Matt Frewer, Nancy Anne Sakovich, Barclay Hope, Joanne Vannicola

Votes: 19

31. Star Trek: The Next Generation (1987–1994)
Episode: Sarek (1990)

TV-PG | 45 min | Action, Adventure, Drama

Legendary Federation ambassador Sarek visits the Enterprise to conclude peace talks with a race called the Legarans. His arrival is accompanied with a rash of unusual emotional outbursts among the crew.

Director: Les Landau | Stars: Patrick Stewart, Jonathan Frakes, LeVar Burton, Michael Dorn

Votes: 3,849

32. The Tony Robbins Podcast (2016– )
Breakthroughs in Immunity: Facts over Fear, Part 1 - Stem Cell Therapy to Treat COVID-19 with Dr. Bob Hariri and Dr. Peter Diamandis (2020 Podcast Episode)

Documentary

Add a Plot

Stars: Anthony Robbins, Robert Hariri, Peter Diamandis

33. Menschen bei Maischberger (2003– )
Episode: Die Fürstin und der Kardinal (2008)

Talk-Show

Add a Plot

Stars: Sandra Maischberger, Joachim Meisner, Gloria von Thurn und Taxis

34. Longines Chronoscope (1951–1955)
Episode: Episode dated 30 October 1953 (1953)

News, Talk-Show

Lesueur and Gilbert Kent, medicine editor for Time magazine, interview C.J. Van Slyke, associate director of the National Institute of Health. Topics include chronic disease, degenerative ... See full summary »

Stars: Gilbert Kent, Larry LeSueur, C.J. Van Slyke

35. Your Home Made Perfect (2019– )
Episode: Liz and Paul (2023)

59 min | Reality-TV

Using virtual reality, two top architects compete to remodel a three-bed semi in Norfolk. Will the couple go for Lynsey's wedge-shaped extension or Damion's explosion of colour?

Directors: Lubna Bhatti, Flora Fenton | Stars: Angela Scanlon, Damion Burrows, Lynsey Elliott

36. Marseille (2016–2018)
Episode: Homme de paille (2016)

TV-MA | 40 min | Drama

Barrés and Taro plan their next step, but a brutal event hits the city. Rachel tries to discover the secret of her husband.

Director: Florent-Emilio Siri | Stars: Gérard Depardieu, Benoît Magimel, Géraldine Pailhas, Nadia Farès

Votes: 186