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Love & Other Drugs (2010)

R  |   |  Comedy, Drama, Romance  |  24 November 2010 (USA)
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Ratings: 6.7/10 from 133,934 users   Metascore: 55/100
Reviews: 211 user | 217 critic | 38 from Metacritic.com

A young woman suffering from Parkinson's befriends a drug rep working for Pfizer in 1990s Pittsburgh.



(screenplay), (screenplay), 2 more credits »
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Nominated for 2 Golden Globes. Another 1 win & 5 nominations. See more awards »



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Cast overview, first billed only:


Maggie (Hathaway) is an alluring free spirit who won't let anyone - or anything - tie her down. But she meets her match in Jamie (Gyllenhaal), whose relentless and nearly infallible charm serve him well with the ladies and in the cutthroat world of pharmaceutical sales. Maggie and Jamie's evolving relationship takes them both by surprise, as they find themselves under the influence of the ultimate drug: love. Written by Twentieth Century Fox

Plot Summary | Plot Synopsis


Accros aux nuits sans lendemain ou dépendants l'un de l'autre? (Addicted to one-night stands or dependent on one another?) (French)


Comedy | Drama | Romance

Motion Picture Rating (MPAA)

Rated R for strong sexual content, nudity, pervasive language, and some drug material | See all certifications »

Parents Guide:





Release Date:

24 November 2010 (USA)  »

Also Known As:

Hard Sell  »

Filming Locations:


Box Office


$30,000,000 (estimated)

Opening Weekend:

$9,739,161 (USA) (26 November 2010)


$32,357,532 (USA) (11 February 2011)

Company Credits

Show detailed on  »

Technical Specs


Sound Mix:



Aspect Ratio:

1.85 : 1
See  »

Did You Know?


The anti-Parkinson's drugs Sinemet and Ropinirole mentioned in the film can cause sexual hyperactivity and hyperarousal in some patients as a side effect. See more »


Trey refers to himself as "an ex-Marine". An actual Marine would never use that phrase. The status of being a Marine is retained for life, hence the motto "Once a Marine, always a Marine". It would have been more appropriate to have him refer to himself as "a Marine veteran". See more »


Jamie Randall: Let's just say in some alternate universe, there's a couple just like us, okay? Only she's healthy and he's perfect. And their world is about how much they're going to spend on vacation or who's in a bad mood that day, or whether they feel guilty about having a cleaning lady. I don't want to be those people. I want us. You. This.
See more »


Featured in The 2011 Comedy Awards (2011) See more »


Macarena (Bayside Boys Mix)
Written by Carlos De Yarza (as Carlos Alberto De Yarza), Mike Triay, Antonio Romero and Rafael Ruiz
Performed by Los del Río
Courtesy of Sony Music Entertainment España, S.L. and The RCA Records Label
By Arrangement with Sony Music Licensing
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Frequently Asked Questions

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User Reviews

not the average romantic comedy ( and thats a good thing)
25 January 2011 | by (Mexico) – See all my reviews

This is one of those movies that have a weird marketing campaign, the studio wants to sell it like a romantic comedy when its more like a drama with complex and real characters. Anne Hathaway and Jake Gyleenhaal have good chemistry on screen and secondary characters help to bring equilibrium to a movie that other way could turn to be a little depressing. I also think that this movie doesn't deserve the R rating just because it deals with sex ( I live in Mexico and here we have something like PG-15)hopefully people don't feel to uncomfortable with the sex scene because it gives more credibility to the story.In the end the film works better than others of its genre and its worth a look ( probably not for a first date) but if you are already on a relationship it will give you something to think and talk about.

47 of 69 people found this review helpful.  Was this review helpful to you?

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