The Oscars will surely knock on Pedro Almodóvar’s door this awards season.

Pedro Almodóvar’s expansive filmography has shaped international cinema for over four decades. With his English-language directorial debut, “The Room Next Door,” fresh off winning the Golden Lion at the Venice Film Festival, the Spanish auteur and distributor Sony Pictures Classics are setting their sights on landing Almodóvar’s first best picture nomination.

Adapted from Sigrid Nunez’s novel “What Are You Going Through,” the film follows two women — war correspondent Martha (Tilda Swinton) and author Ingrid (Julianne Moore) — who reunite after years apart under challenging circumstances.

Read: You can see all Academy Award predictions in all 23 categories on one page on the Variety Awards Circuit: Oscars

Almodóvar’s body of work has garnered widespread acclaim within the Academy. “All About My Mother” (1999) won the Oscar for international feature, while “Talk to Her” (2002) earned him two noms for directing and original screenplay,...