Charmaine from Trinidad suffers from one of the most extreme cases of neurofibromatosis ever recorded. Tumors cover every inch of her body and obstruct her ability to breathe and swallow. Without surgery, these growing tumors threaten her life.
Thirty-year-old Alexandra has a 20-pound, sagging tumor that starts at the back of her neck and now reaches below her waist. As the tumor on Claudia's backside continues to grow, so does the urgency for surgeons to remove it.
Despite his family's pleas, Marlow explores a high-risk surgery to remove a facial tumor. Also, Amy has let the tumor on her back grow for more than 17 years. After finally making the decision to remove it, she learns that now it might be too late.
The bulbous tumor growing from Jennifer's stomach threatens her relationship with her long-time boyfriend. Fifteen-year-old Marcelo travels from Angola to Los Angeles to have a massive neck tumor removed, but the operation may be too risky.
The enormous mass on the back of Arlin's neck and head constantly oozes fluids, but surgery may prove to be too challenging. A tumor on Renae's shoulder and back has caused her to retreat from the public's eye, impacting her job as a care pastor.