After being on the run for 6 months, Richard Kimble falls in love with a beautiful woman who has a young son. She also has a physically abusive, estranged husband, that wants Kimble out of town, or dead.
A friendly country girl has a crush on Kimble and wants to help him escape on the condition she can go with him, as the Sheriff and Lt. Gerard close in on them.
Richard Kimble helps a black boxer realize that he may have a brain injury that will kill him if he continues to box. Meanwhile, an undercover police Sgt. closes in on Kimble.
Kimble and a group of farm workers are surrounded in the hills by a huge fire and he must reveal that he's a doctor in order to save the life of a pregnant, illegal immigrant.
Sailing from Seattle to Alaska, Dr. Kimble finds himself in the middle of a murder mystery. To prove his own innocence, he must play detective to figure out who the real killer is.
Kimble breaks jail with a friendly, simple-minded young man, and finds out the man may have been falsely blamed for a crime he did not commit years ago.
After saving a busload of kids in an accident, Kimble is knocked unconscious and later identified as a fugitive. Gerard comes to this Massachusetts town to extradite him back to Indiana, much to the dismay of the town's grateful residents.
Working at a remote construction site, Dr. Kimble tries protect a coworker with a low I.Q. from being lynched when the caring married woman who's been teaching him to read, is assaulted by an unknown attacker.
A pretty airline stewardess badly injures Kimble in a traffic accident, and in his delirium, he admits who he is and she helps him. In turn, Kimble helps her realize the married man she's dating is not right for her.