Sineaters is the story of a lone drifter who has come to the end of a violent and bloody journey. He has the power to consume the sins of evil-doers, and the power to heal with his hands, part faith healer and part gun slinger. He loses the spiritual struggle with the Grim, a manifestation of all the evil he has removed from the world, and is turned against his sineater comrades by the cult known as the Vessels of Wrath. Working with a twisted preacher, Brother Aaron, and a darkly alluring woman who seems to guide the preacher's every decision, the sineater hunts down his friends one by one, as the battle for his soul rages on.