Sean Gunn's cameo role as Doctor What was inspired by John Hurt's role in the Doctor Who Anniversary Special and how it made John Hurt an official Doctor by simply playing the character just one time. The Joke is that when James Gunn would have a dirty job that nobody else wanted to do on the set of his movies, he would simply say "We'll just get Sean Gunn to do it". Hence, Sean Gunn's Doctor What is so maligned, that he only gets to play Doctor What when the other Doctors are too busy, and he gets fired thirty minutes into the film in favor of Stephen Geoffreys.
The original Afterlife Q&A scenes in the Fan Fiction series between Kevin from the Other Dimension and The Angel were inspired by Roy Scheider's conversations with a God in the Bob Fosse movie All That Jazz. In the film, God is played by a woman. In the Bad Goddess Cartoon Adaptation, these two characters were changed to Charlie Day and Lind the Valkyrie. Confusingly, Charlie Day is not Kevin from the Other Dimension in this movie. Charlie Day is Doctor What doing a script reading of Kevin from the Other Dimension's lines from the Fan Fiction screenplay and even points out when Lind's dialogue deviates from the script he was given. The part where it is explained that Kevin from the Other Dimension commit suicide was a deviation from the Original Story, and was written into the Video Comic Adaptation due to the unexpected real life suicide of Kevin Neece's nephew Dylan Guitierrez. It also brings a new Allegorical meaning to the chapter Once There Was a Boy where the Keys of Marinus Gang become an Allegory for the Angels of Judgment, telling the story of Kevin from the Other Dimension's life to determine if he is to be sent to Hell as punishment for taking his own life. Once There Was a Boy ends with a memorial for Dylan Gutierrez and basically stops the movie dead in it's tracks, even thought there are two more chapters left to go. Dylan's mother, Carrie, approved of his memorial in the film, even though she probably didn't understand the movie itself.