Chris visits Thailand to help a young elephant mother that doesn't produce milk, an old elephant with an infected zit, an endangered gibbon that may be pregnant, and a group of traumatized dogs rescued from the dog meat market.
Dr. Chris is called to South Africa where he must perform surgery on a trio of lionesses. While there, he helps de-horn an endangered white rhino to keep the poachers away and races to replace the tracking collar on a female elephant.
Dr. Chris Brown saves fur seals off the coast of Australia who have been entangled in fishing wire. Chris then travels to Fiji to tag bull sharks who are being fished in a local river and must help a badly injured pig who was attacked by dogs.
Dr. Chris sets off to Vietnam, where he must perform surgery on two endangered turtles. Chris then works with an adorable langur and a very ill baby loris. Later, Chris treats a group of smuggled Pangolins are on the brink of death from hypothermia.
Returning home to Australia, Chris investigates a deadly disease that's killing koalas. Then, deep in the remote Northern Territory, he helps an aboriginal town that is overrun by dogs, and a kangaroo with an infection.
Dr. Chris visits Namibia where he works with the cheetah population at the N/a'an Ku Se Wildlife Sanctuary. He also visits a baboon who may have brain trauma. Later, Chris gives a health check to some meerkats before releasing them back to the wild.
In Tasmania, endangered Tasmanian Devils have been dying from a rare form of cancer and Dr. Chris must help save them from extinction. He also helps rescue an injured pademelon, and then helps wombats suffering from severe cases of mange.
Dr. Chris travels to Costa Rica to help a sloth who suffered a life-threatening injury. Then, he captures and helps a capuchin monkey with an unidentified skin disease. Chris also treats dogs with a mite infestation at "Territorio de Zaguates".