Goofs

When Sheldon cleans the house, he is shown putting on rubber gloves, first pulling on his left glove with his bare right hand, then putting on his right glove with his once again bare left hand.

When Sheldon is vacuuming, Missy is sitting on the couch. Her legs go from one tucked up to both legs down, then back to one tucked up, without ever actually moving.

Sheldon says his Prefrontal Cortex is enormous, but the Prefrontal Cortex is responsible for personality, decision-making and social behavior. The Frontal Lobe is responsible for thought and logical reasoning.

Throughout the series Sheldon occasionally gets his facts wrong. Here he dismisses "Atlantis" as the best Space Shuttle name by claiming that it was an island that "couldn't even stay afloat". Islands don't float.