Goofs

In The Scavenger Vortex (2013) Bernadette gets real mean and shows no mercy when competing in the scavenger hunt...but starts to freak out when Denise starts yelling at her while being shown how to play Fortnite.

When Sheldon and Amy are sad because their super asymmetry theory was disproven, they point out that they've been wrong twice that week. Amy says that 'Professor Gregoropovich' was what happened to them as he disproved their theory. Leonard then corrects them, saying he thinks it's Gregoro-poli-popovich'. Amy then says 'three'. Sheldon should have remembered his name as he has an eidetic memory.

Most scientists would study a paper with a conflicting theory to either disprove or use its research in their own work before just giving up like Sheldon did.

Amy and Sheldon would publish a paper on a groundbreaking subject in a respected academic journal. As these provide template documents with obligatory fonts and sizes, choosing a custom font is futile, something both of them would know.

When Bernadette asks to join Howard playing Fortnight, Howard makes two comments about things that were said on their honeymoon. Howard and Bernadette never had a honeymoon. He went to the International Space Station right after they were married and when he got back Bernadette was ill.

Or, they did have a honeymoon after Bernadette got better, and it happened off-screen.