John Candy who had a cameo appearance, was actually the original choice for Louis Tully in the movie Ghostbusters (1984). Eventually he was played by Rick Moranis.
The clip's cast includes two Oscar winners: Irene Cara and Carly Simon; and seven Oscar nominees: Ray Parker Jr., Danny DeVito, Bill Murray, Dan Aykroyd, Sigourney Weaver, Peter Falk and Teri Garr.
The order of the apparition of the cameos in the music video is:
-0:43 - Al Franken.
-1:16 - Chevy Chase.
-1:26 - Irene Cara.
-1:58 - John Candy.
-2:23 - Melissa Gilbert.
-2:32 - Ollie Brown.
-3:26 - Jeffrey Tambor.
-3:30 - George Wendt.
-3:34 - Al Franken (again).
-3:43 - Danny DeVito.
-3:47 - Carly Simon.
-3:51 - Peter Falk.
-3:55 - Teri Garr.
-3:58 - Chevy Chase (again).
-0:43 - Al Franken.
-1:16 - Chevy Chase.
-1:26 - Irene Cara.
-1:58 - John Candy.
-2:23 - Melissa Gilbert.
-2:32 - Ollie Brown.
-3:26 - Jeffrey Tambor.
-3:30 - George Wendt.
-3:34 - Al Franken (again).
-3:43 - Danny DeVito.
-3:47 - Carly Simon.
-3:51 - Peter Falk.
-3:55 - Teri Garr.
-3:58 - Chevy Chase (again).