In an age of men and beasts, centuries of war have left much of the world toxic, sick and uninhabitable. Mutants and half-men wander the globe. Civilization has crumbled and the survival of the human race is uncertain. In an attempt to seize control of the planet, the evil Mad Doctor Mindskull lays plans to acquire the Nova Seed and harness the earth's very life essence to turn himself into the ultimate weapon. With nowhere left to turn, a fading humanity places it's last hopes of defeating Doctor Mindskull in a genetically modified NAC (Neo-Animal Combatant).