Elizabeth Henstridge and Iain De Caestecker reprise their roles as Agents Jemma Simmons and Leo Fitz from Marvel's Agents of S.H.I.E.L.D. (2013). They originated in the Marvel Cinematic Universe alongside Agent Coulson.
Jemma and Fitz appear in the outfits that they wore in the pilot of Agents of S.H.I.E.L.D. (2013), their first ever appearance.