Near the end, Mac asks Daisy for back-up on Halo 5: Guardians (2015). Halo 5 has no 2 player/split screen, so that would not be possible.
The banner in the Alston pub reads, "Boston Red Socks." This is never correct in modern times, it is always "Red Sox." However, this change likely was made to avoid infringing on the Major League Baseball trademark.
When Coulson and the team are watching the broadcast on T.V., the announcer states "The suspect is considered dangerous and is wanted by both federal employees and the A.T.C.U." The closed caption however, reads, "The suspect is considered dangerous, he is wanted in connection to a terrorist attack."
Fitz talks about the planet Simmons was on possibly having "different microgravity." The planet may have had different gravity, but microgravity is what you would have in an orbiting vehicle; it's the technical term for what the layman would call weightlessness.
Simmons says that she's "still acclimated to less gravity." Simmons is English; she would have said "acclimatized." She's also a scientist; she would have said "lower gravity."