In her opening monologue, host
Chelsea Handler talks about the latest person who has changed her mind about needing smarts to do a specific job. Chelsea and her round table panelists
Josh Wolf,
Loni Love and
Gary Valentine discuss
*NSYNC getting together for a one night only performance,
Alex Rodriguez's status as one of the most hated personalities in major league sports, a New York Post article that states the US has the most online porn domains in the world, Virgin Atlantic Airlines having live entertainment on their flights, and a study that reports that one in four dogs is depressed. Chelsea tests Chuy's knowledge of back to school basics. And Chelsea presents Regina the Makeup Lady who likes to talk about her life.
—Huggo