Medulla, the humanoid with an eyeball for a head is homage to the band, The Residents.
The lawyer shark character is a tribute to the shark from Jaws that Spielberg named Bruce, who was his lawyer at the time.
Jack White makes an animated cameo in the video as the character, Mikey, whom he played in the film Mutant Swinger from Mars, which is where this track is from.
Various characters that make animated cameos in the video include, Ash and Linda of Evil Dead 2 and The Evil Dead and Grandpa Munster from Rob Zombie's The Munsters. The director, Michael Kallio also happens to be friends with the three actors (Bruce Campbell, Betsy Baker and Daniel Roebuck, respectively) mentioned that appear as their animated character counterparts in the video.
The long, two-eyed aliens look very similar to aliens created by Andrew Clement and Michael Kallio for a travel show pilot Kallio directed called Travelin' Time back in 2019.