In an exterior scene of the film the cast/crew shot a night scene which is to play a summer night when it began to rain, turning into snow. The cast wore short sleeve shirts and tank tops, while the crew was dressed in gloves, thermals, heavy coats and scarfs.
Story takes place in the same fictional village all DefTone films are set in "Metzburgh" Originally from first version of Gore.
Metzburgh High School in Ombis is actually Hamburg High School located in Western New York. The director Adam R Steigert graduated from the same school in 2005.
When Rookie officer Brian Higgins enters the class room in Metzburgh High with Mark to speak with Professor O'Neil about their latest horrific findings, written on the caulk board is the formula to make Ombis Slime.
The day after the Ombis crew wrapped on an intersection in Angola New York. which is featured in the film during in epic battle between the hero character Mark and the alien bounty hunter Nemesis the crew left huge amounts of fake blood on the street and the following day showed up to scrub the village's intersection. The crew was a four man team and took approximately four and half hours to clean.