The Transylvanian representative at the UN is named C. Cjokula, a reference to Count Chokula.
Dr. Leo Spaceman's line to Jenna about being considered a monster due to having teeth in a different part of her body is a reference to the 2007 film, Teeth.
Kirsten Schaal and Mary Steenburgen also appear together in The Last Man on Earth which stars Will Forte.
The scene where Kenneth and Hazel are in Tracy's dressing room with the GPS tracking sensor for the lizard is a parody of the scene in Aliens where Ripley says "that's inside the room" when they are tracking the approaching xenomporphs with the motion tracker, who are also in the ceiling.