Michelle Hurd (the bar owner) is married to Garret Dillahunt, who played John Dorie on Fear the Walking Dead (2015).
The New Babylon wanted poster for Negan Smith reads, "If you have any information on this man, notify any office of the New Babylon Marshals. Do not approach unless armed. Antisocial, prone to extreme violence. With above-average intelligence and charisma. Do not trust him...any action to evade justice."
With this episode taking place years after the end of "The Walking Dead", Logan Kim takes over the role of Hershel Rhee. The role was previously played by Kien Michael Spiller.
It was stated that all the bridges and tunnels to Manhattan were blown to stop the spread of the infection to the rest of the country. There was a similar plot device to another zombie-themed film starring Will Smith in I Am Legend (2007), which was also set in Manhattan. The film was based on the novel of the same name by Richard Matheson. The novel inspired other films such as The Last Man on Earth (1964) starring Vincent Price and The Omega Man (1971) starring Charlton Heston.
Trey Santiago-Hudson, who plays the Deputy Marshal Jano, is the son of Ruben Santiago-Hudson, whose most well-known as Captain Roy Montgomery in Castle (2009).