Plot

Sam and Dean go to Missouri to track down a shapeshifter that kills its victims by taking on the shape of their loved ones.

In Missouri, Sam and Dean track down a shapeshifter that has killed five victims. In each case, it takes on the form of a victim's loved one, killed, and then left its duplicate to take the blame. But when the Winchesters become separated and then reunite, they soon realize that one of them is the creature they're hunting.—Gislef

Sam gets an e-mail from his old school friend Becky telling that her brother, Sam's friend Zach, is arrested in St. Louis for the alleged murder of his girlfriend. Zach claims that he was in another place at the same time, but the surveillance camera had taped his image in the crime scene. Sam convinces Dean to drive to Missouri, to check out the apparent doppelganger case, posing as US Marshalls. Once there, they find that a shape shifter is killing and hurting people in the neighborhood. When the ghost demon takes the form of Dean, things get complicated for Sam who soon realizes it's not his brother.—KGF Vissers

While looking for their father who has disappeared, demon hunters Sam and Dean start to investigate a bizarre string of murders in which husbands are being accused of killing their wives. The brothers head to a town in Missouri. While the suspects are the husbands and there's evidence that supports that they did it, all of them insist that they are innocent. Sam and Dean think that it might be the doing of their Ikiryou (from Japanese mythology - a vengeful manifestation of part of a living person's soul) and start the investigation, however.—theTVDB