The mayor mentions that cell phone towers have been turned off near the end of the film. Yet, people are able to use Facetime on their phones during the movie, even at the end after he says this.
The CDC head mentions that they need to investigate the divers during the film. But they are not informed about the divers until later, at the end.
The news anchors are wearing the exact same cloths weeks apart. When they first report on the death of the divers, and then on the 4th during the actual outbreak.
There's an external shot (56:25 into the movie) in total darkness, captioned '8.58pm, July 4th' There's no way it'd be pitch black at that time, on that day of the year in Maryland, where the film is set. The sun only sets at 8.35pm on that day of the year at that latitude.
Video time stamping generally uses a 24h format and, for police video, always. What was shown in the police video as 09:45 would have read 21:45.
The law enforcement agency in Claridge is shown to be the "Town of Claridge Sheriff". However, in Maryland, sheriffs are elected at the county level. There are no sheriffs for municipalities. The only exception would be the City of Baltimore, which is treated as a county under Maryland law. Claridge would likely have its own municipal police department or be patrolled by the county's sheriff department.
When Stephanie is getting into the front seat of the cop car after leaving the antique store, cars are being driven through the back window, even though the roads to Claridge were suppose to have been cut off.
When the medical issues first appear, a doctor tells the patient to state her name for the camera. Lamya Reynolds says her actual maiden name (Lamya Jezek) even though her character is listed as Ms. Rosenblatt.
The events take place in 2009. One of the characters shows her symptoms via FaceTime which did not debut until 2010.
Narrator states that the instance of something wrong was 6 weeks before July 4th. The footage that accompanies this statement is dated June 18th, clearly not 6 weeks before July 4th.
The cars on the bridge have South Carolina plates and South Carolina palm and crescent stickers. The movie's story took place in Maryland. Some of the film was shot in South Carolina.
Around the beginning, the mayor drinks a cup of water. However, he never ends up becoming infected.