In Argentina, after an economic crisis, a drug epidemic has spread to the capital Buenos Aires. The suburbs have turned into ghettos where no police officer dares to enter.
In the Brazilian city of Rio de Janeiro, a daily war is going on between gangsters and the police. Ewout has access to a neighborhood where cartels rule. He experiences for himself what it is like to have to live there.
Panama is a popular place for drug cartels due to its central location. Ewout meets gang members who kill people on assignment. They get hold of a drug thief and want to kill him in a gruesome way.
Miami's tropical beaches are world famous, but the city also has a huge drug problem. On the way to the ghettos, Ewout is already confronted with a shooting incident.
Ewout travels to Medellín, Colombia. Street gangs that control the entire neighborhood are active here. They control the local and sometimes international drug trade.