Fentanyl is a real drug first synthesized by Paul Janssen in 1960. Fentanyl (also known as fentanil) is known by brand names Sublimaze, Actiq, Durogesic, Duragesic, Fentora, Matrifen, Haldid, Onsolis, Instanyl, Abstral, Lazanda, etc, a synthetic opioid analgesic with a rapid onset and short duration of action.Historically, it has been used to treat breakthrough pain and is commonly used in pre-procedures as a pain reliever as well as an anesthetic in combination with a benzodiazepine. Fentanyl is approximately 80 to 100 times more potent than morphine and roughly 40 to 50 times more potent than pure) heroin.