Hugh Laurie makes his American television directorial debut in this episode. He also directed The C Word (2012).
The Latin phrase on a poster on the wall means "Everyone loves you when you're about to die."
House's personnel file indicates that his physician and emergency contact are both Wilson.
Jennifer Morrison and Jesse Spencer were together in real life. After they met on their way to film the pilot and dated throughout the first three seasons, they became engaged halfway through season three but broke up shortly before season four. Hugh Laurie noted that he shed a tear as Cameron tells Chase she isn't sure she ever loved him.
When Foreman reads Taub's file, he learns Taub led a group of surgeons in fixing cleft palates in Bangladesh. Taub replies that "the concert was very moving to me." Taub is referring to The Concert for Bangladesh, a two performance, multi-musician concert organized by George Harrison in 1971 when his friend Ravi Shankar expressed a desire to help refugees from East Pakistan after the genocide of the Bangladesh Liberation War.