Later in the film, when Dimitri attempts to strangle Angel with his belt, she stabs him with a syringe loaded with heroin. He almost immediately reels back, loses coordination, and begins vomiting. The first issue with this is the method of injection. For heroin (or any drug) to have a near-immediate effect when injected, it must be intravenously (IV) injected, i.e., directly into a blood vein. With Angel jabbing the needle randomly into his leg like she does, the chances of hitting a vein directly or hitting and not going through are slim; more likely, the needle will pierce muscle tissue and be injected intramuscularly (IM), a method which will result in a much longer and milder onset of effects.
Also, assuming the dose Angel draws into the needle is comparable to what she normally gives the girls, it likely would not effect a large man the same way it would the smaller girls; specifically, Dimitri probably would not have experienced vomiting and coordination loss to the point where he couldn't stand straight. However, it might also be assumed that the girls have been there a while and have developed a tolerance for the drug, resulting in a larger dose being necessary. If this were the case, the dose might be enough to affect Dimitri in such a manner, assuming he doesn't use heroin on a regular basis himself.
Also, assuming the dose Angel draws into the needle is comparable to what she normally gives the girls, it likely would not effect a large man the same way it would the smaller girls; specifically, Dimitri probably would not have experienced vomiting and coordination loss to the point where he couldn't stand straight. However, it might also be assumed that the girls have been there a while and have developed a tolerance for the drug, resulting in a larger dose being necessary. If this were the case, the dose might be enough to affect Dimitri in such a manner, assuming he doesn't use heroin on a regular basis himself.
The movie takes place in 1996 yet the wad of money contains the redesigned 5 dollar bill which didn't come out to 2008.