At the Three Rivers Hospital in Pittsburgh, a clinic specializing in organ transplants, Dr. Andy Yablonski is the highly-skilled workaholic lead organ transplant surgeon, whose good-natured personality and sarcastic wit makes him popular with both his patients and colleagues. His co-workers include Dr. Miranda Foster, a surgical specialist with a rebellious streak and fiery temper who strives to live up to her deceased father's excellent surgical reputation; Dr. David Lee, a womanizing surgical resident who's broken as many hearts as he's replaced; Ryan Abbott, the inexperienced new transplant coordinator who arranges the intricately choreographed process of quickly and carefully transporting organs from donor to patient; Dr. Sophia Jordon, the dedicated head of surgery who has no patience for anyone who hasn't sacrificed as much as she has for the job; and Pam Acosta, Andy's no-nonsense operating assistant and best friend. In the season opener, a young pregnant woman's life hangs in the balance when she suffers a massive heart attack and Andy tells her that the only way to save her is for her to undergo a heart transplant. When complications arise with the donor's family, whom is a fatally injured construction foreman, Andy races the clock to save not only her life but that of her unborn child.
—matt-282