- Lightning Wilcox: I didn't shoot Jaws.
- Detective William Murdoch: Well, someone did.
- Lightning Wilcox: Yeah, someone did, and whoever they are, I'll find 'em, and when I'm done, their boots'll be pointin' up toward their maker. You mark my words.
- Detective William Murdoch: Mr. Wilcox, how many men have you killed?
- Lightning Wilcox: Countin' Indians? Beats me. Somewhere between plenty and too many, I guess.
- Annie Oakley: [to Brackenreid] A friend of mine once gave me a piece of advice. He said, "Don't try to be good. Try not to be bad."
- Inspector Thomas Brackenreid: [Not wanting to wear the garish cowboy hat that Murdoch has won at the lassoing booth] I'd need about four large scotches inside me before that came anywhere near my head, me old mucker.
- Detective William Murdoch: [to Buffalo Bill] Sir, the West is dead and gone. There's nothing left of it now but a carnival show.
- Buffalo Bill Cody: [Realizing that Murdoch suspected he was lying about his poor eyesight] And you thought I was lyin'!
- Detective William Murdoch: With all due respect, Mr. Cody, you've built a whole show around lies.
- Buffalo Bill Cody: Well, people don't want the truth. No, sir, they want something else. They want a good story, and a good story told often enough... that can become the truth.
- John Warton: I'm not above turning a dead man in for a thousand dollars. I'm not above stealin' his gold teeth, but I didn't kill One Tooth... that's my word.
- Inspector Thomas Brackenreid: I have to ask you where you were when the shot was fired.
- Annie Oakley: I was in my tent. Alone. But I didn't shoot Jaws. Oh, if I'd 'a shot him I'd 'a aimed a lot lower than his teeth.