Suarez says, and Chloe agrees, there are documented cases of lycanthropy, very rare and very dangerous. This is disingenuous; there have been a few cases of psychotics believing they transform into wolves but those people were simply delusional, and not particularly dangerous. The classic image of a mental patient believing he is Napoleon, without either transformation or invading Belgium, is functionally the same as the 'documented cases of lycanthropy'.
The closing scene shows Jack and his duffle bag in a plaza. The location is the Plaza de Bolivar in Bogota, Colombia. Although the entire season was filmed in Bogota, this is the only scene where you can readily see that.