This cult comedy centers around Damian a half-human, half bear child, raised sheltered in an Old World fashion by his "Mama", a dominatrix and human behavior researcher, his step-father, Gunter (a gentleman drunk), and his new nanny, Wolfgang, Gunter's nephew and world-traveling deviant. Damian befriends Preston, a trailer-trash kid from the neighborhood. There the trouble/adventure begins. Other characters appear including Opa, the Nazi grandfather chained in the basement, Hans Bobbie, Damian's arch nemesis, and Jolene, Preston's sister, whose big toe is her partially digested twin. Mama holds the family together, but she becomes unraveled when Damian gets into too much trouble. Mama and Damian is, on the surface, a fable about an innocent wading into treacherous waters, but there is also an underlying theme about what it really means to be an American and why one man's freak is another man's normal.
—Kathi Lehmer