Through Gwen's inherited abilities, Helen calls out from the Null Void for help. Entering through a portal of Gwen's creation, Ben finds himself on the losing side of a battle. His old nemesis, Dr. Animo, has taken over that world under the new name of D'void. Only a small resistance group composed of Plumbers' Helpers stand against him, lead by The Wrench (none other that Grandpa Max). Ben's arrival comes none too late to try thwarting D'void's/Animo's plans to break his gathered army of alien creatures back into our universe.
—statmanjeff