On more than one occasion, Pogo is referred to as a "monkey". Pogo is a chimpanzee and therefore classified as a "great ape".
Diego, Lila, Five, Viktor, Sloane, Ben, Klaus and Luther lose their powers when Reginald sucks out all the Marigold inside their bodies in the end of season 3, but in season 4, Allison doesn't have her powers either, even though she was not included in this process because of her deal with Reginald.
In season 2, it is revealed that Reginald is an alien wearing a silicone mask undercover as a human but earlier in season 1, when young Vanya and him are training with sound waves in the house, she breaks his monocle and his face bleeds.
Set in US but the majority of vehicles are right hand drive.
Lila has a thick British accent even though the Handler raised her from the age of 4 and no one else in the commission had an accent.