Plot

Thirteen's one night stand collapses at her apartment, and her symptoms are so misleading that the diagnosis may be terminal. Meanwhile, revelation about Wilson and Thirteen occupy House.

We opened on Thirteen (Olivia Wilde) having a hot make out session with another girl. Spencer (Angela Gots) in her apartment -- and it isn't even sweeps week!

Soon enough, the nameless girl had a seizure after they'd had sex, which was undoubtedly going to leave Thirteen with some explaining to do once House (Hugh Laurie) got hold of this story. Thirteen, it turned out, didn't know the girl's name and the patient had mixed ecstasy with alcohol. House and Foreman (Omar Epps) asked Thirteen if she'd also been doing drug and she said, "Not diagnostically relevant." Thirteen, Kutner (Kal Penn) and Taub (Peter Jacobson) all thought the problem was easily explained by blood clots, but House wanted more tests.

House sat in as Thirteen injected her friend with a massive needle to get some bone marrow. He asked several probing questions about the patient's evening with Thirteen that made Thirteen uncomfortable.

House had his private investigator -- remember that guy? (Michael Weston) -- look into where Wilson was earlier that morning because he was afraid Wilson (Robert Sean Leonard) was lying to him about where he'd been. Wilson's back at the hospital, by the way.

Thirteen, also known as Dr. Hadley, discovered her patient/lover had used her to get House to figure out her undiscovered illness. Thirteen wondered if the woman had faked the seizure, but she said she wouldn't have faked a symptom because that would have only made it harder for House to do his job. Thirteen still didn't believe there was anything seriously wrong with the woman and wanted to discharge. Thirteen said House was using the patient to get information on her personal life. Then the patient crashed.

House rubbed Thirteen's nose in the fact she was wrong about the patient, then he suggested she was just jealous of him because the whole time the patient was with her, she was really thinking about his "huge, throbbing ... diagnostic skills."

House figured out the patient was a serious drug user, which upset Thirteen. She was mad because she knew that meant the woman's seizure was set off by something she'd done at Thirteen's house, which meant House was going to go through her house. Thirteen refused to give him her keys, though, so he had Foreman come along to pick the lock. But he couldn't, which prompted House to tell him, "You're a disgrace to your stereotype." House opened the door with a key he'd had his private investigator make.

House found a brown recluse spider in Thirteen's apartment, which could have caused the seizure and heart problems if the patient had been bitten. He had Thirteen examine her for a spider bite. Thirteen told the woman she didn't intend to see her again, but the woman suggested they had potential for a relationship. Then Thirteen realized the woman's hip was numb, which meant it wasn't a spider bite.

House staked out Wilson's place with the private investigator and saw that Wilson appeared to have hired a prostitute.

Foreman, who knew Thirteen was afraid of what House might have found at her place, told Thirteen he'd found it. It was the result of a recent test showing her Huntington's Disease was more advanced than she'd thought, which meant she had less time. Foreman told her to do things to make her better, but Thirteen decided doing drugs and having sex with strangers was her way of having fun, "cramming as much life into my life as I can."

After the patient stopped breathing during surgery, House and the crew went over more possibilities, but Thirteen was missing. We saw her in an exam room, having hooked herself up to an IV. She answered a knock on the door by saying there was an exam going on, but the door opened anyway. It was Cuddy (Lisa Edelstein), and she didn't look happy.

Cuddy told House about Thirteen hooking herself up to an IV for fluids and Cuddy wanted Thirteen to take a drug test. House defended Thirteen and said she didn't have to take the drug test. Then he fired her. She was shocked, but he told her he just wanted to save her from taking a drug test, which probably saved her career. He said he was "already taking responsibility for one doctor with a drug habit," as he popped a couple of Vicodin.

Wilson admitted to House he started dating a woman who "used to be" a prostitute. She wanted to become a lawyer and he told her he'd help her pay for law school.

Thirteen was going through the patient's X-rays in hopes of coming up with something that could save her job. She realized the woman had a cyst that threatened to explode her lung if the doctors continued with a treadmill test they were doing. She raced to where Kutner and Taub were doing the test, where she found them trying to figure out why the patient couldn't breathe. She explained the patient's lung had collapsed and she jammed a syringe into the woman's chest, allowing her to breathe again.

House told Thirteen "my employees can take it from here." Foreman and Taub tried to talk him into giving her job back, but he'd have none of it. He asked Thirteen how much clearer he had to make himself. She walked out.

House and the PI talked about the Wilson issue, and House said Wilson had a Messiah complex and wants to save women.

House told Thirteen her recent exploits were about control rather than just having flings. Then he told her that the patient has Lam, a disease that gives her cysts and will continue to come back even after removal and will eventually make her lungs stop working. She had 10 years to live, and House wanted Thirteen to give her the news, even though it didn't mean she'd get her job back. She said she'd do it because she knew what it was like to get that news, and, she told him, "no one should have to get it from you." She broke the news to the patient, and said, "I'm so sorry."

Thirteen told the patient about all the stages of grief she'd go through after getting her terminal diagnosis. They decided they'd race to the finish. Thirteen said she'd come back later, but noticed blood out of the bandages around the patient's chest, which was a new symptom that took Lam off the table. Thirteen told the doctors this, leading House to wonder if "fired" has a whole other definition that he's not aware of. Thirteen said he didn't have to pay her, but she wanted to finish the case. She went to help do more tests, but House told her, "you're just a visitor."

Foreman asked Chase (Jesse Spencer) if he thought Foreman was boring, because House had his private investigator look into Foreman and found he hadn't done anything interesting since he was 17. Chase confirmed that, indeed, Foreman is boring.

House told Thirteen the patient needed a bone marrow transplant and asked Thirteen to get the woman's consent.

The private investigator handed House a bag of Wilson's trash, which included some used syringes. "He's using," the PI said. House smiled, walked into Wilson's office and praised him for his craftiness. The syringes, the prostitute, all of it was made up because Wilson knew House was having him followed. House still wanted to know where Wilson was that morning, and Wilson, knowing House would just keep having him followed, told House to be outside his house at 8 o'clock that night.

Thirteen told House the patient said yes to the transplant. House told Thirteen she was in a downward spiral and that she was going to push people away until she died. But until then, he could use her because she did good work. She realized he was trying to save her, making her spend time with the woman to forge a connection.

House noticed Thirteen's lips were cracked and deduced the patient was suffering from Sjögren's syndrome, an auto-immune disease which caused her tears and saliva production to dry up and made her mouth vulnerable to a yeast infection, which she had passed to Thirteen. Sjögren's explained the patient's other symptoms, including the lung cysts, and Thirteen's dry lips. It also meant the patient was no longer going to die, and House prescribed treatment for the disease. Thirteen later admitted to Foreman that now she suddenly felt alone.

House followed Wilson that night -- to a baby store where Cuddy was shopping for a crib. She told him she was adopting a baby and had used Wilson as a character reference, and that's where Wilson was that morning. House looked stunned by the news and when Cuddy asked if he was going to congratulate her, he said, "If you're happy, I'm..." Then he walked out.

Back at her house, Thirteen was hooking up with another strange girl (Helena Barrett).