Kenny Omega and Chris Jericho were opponents for the second consecutive Double or Nothing main event. In 2019 they competed in an AEW World Title qualifier, and in 2020 they represented The Elite and the Inner Circle respectively in a Stadium Stampede match.
Sammy Guevara was in the first ever AEW match, losing to Kip Sabian on the Double or Nothing 2019 Buy-In show. Just a year later he was in the main event of the PPV.