The discussion of Kate, Alice, and Mary's blood types creates some wrinkles with the previous episode, where blood transfusion was also a plot point. If Alice is O- as stated here, and Mary has B-type blood, then Mary's blood should not have been able to be given to Alice or Beth in the last episode without risking complications that, while not necessarily fatal, would still keep the recipient very sick and in need of immediate medical attention.
Ketamine can be effective in seconds, but only if administered intravenously. Nocturna biting Kate on the lip would be more of a subcutaneous administration and taken at least 15 minutes to work, not seconds.
Alice claims that her blood type is O negative and Kate's is A positive. Since the two of them are supposed to be identical twins, they should have the same blood type.
Kate and Beth/Alice are very obviously NOT identical twins. They are fraternal twins and therefore could possibly have different blood types.
Kate and Beth/Alice are very obviously NOT identical twins. They are fraternal twins and therefore could possibly have different blood types.