In the scene where Lily spends the night with Ryle for the first time, she is seen wearing a low-back dress. However, when she undresses, she is wearing a bra with visible straps, which would have been noticeable earlier given the dress design.
The first night just before Ryle and Lily spend the night together, Rtle takes off his pants twice.
When Ryle was taking the burnt frittata out of the oven he should have been wearing an oven mitt.
When the camera is filming Lily Bloom in the mirror her mole and heart tattoo are on the opposite sides as when the camera is filming her direct on. The mirror shots show her face mole on her left side of her face and her heart tattoo on her right collar bone. The mole and tattoo can't change sides.
After Ryle takes the frittata out of the oven and drops the glass pan, his hand is cut and bloody. Seconds later he puts the same hand on Lily's face and leaves no blood behind.
When she asks him what he is doing after graduation he says "basic training in the Marines" Marine training is called "boot camp" and is anything but basic.it is significantly more rigorous and demanding compared to the basic training of other military branches.
When Lily is in the hospital after she has been bitten, when they first show the tattoo and the bite area you can see x's where the bite marks are supposed to be where they missed a frame of CGI.
With Ryle's career as a brain surgeon he would have been aware of how smoking can affect the brain with risks of strokes and cognitive damage.
When Lilly is holding baby Emmy after she was born she calls her "Bubba" which is a nickname or term of endearment that is typically given to males.