George and Izzie drink from a bottle marked "Door River". There is no such thing as the "Door River" brand: the bottle shape and label type are actually "Knob Creek" Whiskey designs.
Every episode of the show is named after a famous song. "Scars and Souvenirs" is a song by Max Stalling.
Jeff Perry (who plays Thatcher Grey) and James Gammon (who plays Mr. Scofield) both were regulars on the tv show Nash Bridges (1996-2001), playing Inspector Harvey Leek and Nick Bridges, respectively.