At the beginning of the episode, Monk looks at the directory to find Dr. Whitcomb's office. In the next scene, an elevator bell dings, and Monk seemingly has just emerged from it. Throughout the series, however, Monk has a severe fear of elevators -- this phobia would not be forgotten even though he has a nosebleed.
The doctor was viciously hit three times with the oxygen tank, but his corpse showed almost no trauma.
The bag labeled tetracycline contains a red solution that looks like tomato juice.
Tetracycline is yellow and would form a yellow solution.
Mr. Monk speaks with a janitor mopping the floor. The mop is completely dry.
When Monk finds the "dead" doctor on the floor of the office, it's obvious the actor is still breathing because his stomach rises and falls. Some scenes later doctor is again seen breathing, and this time he is also seen blinking his eyes.
After Dr. Scott beats up Monk, he tells Monk that the name on his chart is Mr. Butterworth. Yet when Natalie goes to the hospital to rescue Monk, she goes to the ER desk to ask for Adrian Monk. She is then directed to his room - the room that should be occupied by Mr. Butterworth.
Throughout the episode, Monk is tilting his head back because of his bloody nose. This in fact is a common misconception of first aid treatment for bloody noses. The correct treatment is to instead tilt the head forward while sitting upright so that the blood does not run down the back of the throat (a position which may cause gagging, coughing, vomiting or choking). Considering he was in the hospital for quite some time, you'd think that at least one doctor or nurse (especially the two that treated him) would take the time to correct this even though they were busy. The patient should also have an ice pack to the back of the neck, sit straight up, head forward.
When Natalie tells the nurse that Monk is in pain, she hangs an IV bag of tetracycline saying "This should help." Tetracycline is an antibiotic, not an analgesic.
When the team first questions Dr. Scott in his hospital bed, he tells them Hank Johansen couldn't have done the crime because he has progressive rheumatoid arthritis.
Later, in the room with the residents, he describes Mr. Johansen as having osteoarthritis.
When Dr. Scott is discussing the woman with appendicitis with his team, his white coat only reaches his thighs. In medicine, students wear the short coats, while residents and attending physicians wear long coats reaching the knees. Insignificant, but a little jarring to someone used to old-fashioned hospital hierarchy.
When the nurse is starting Monk's IV medicine, she hooks the tubing directly to his IV access without having bled the line first. When hooking up any IV line to a patient's access, the tubing from the bag is first bled with the fluid in the bag to eliminate any air from the line. The only time what the nurse did here would not have immediately killed the patient with a huge air embolism would be if she piggybacked the new fluid onto an already existing bag of fluid, usually normal saline running to keep the line open and patent. But she still would have bled the piggyback hook up first before attaching to a port on the existing tubing. Monk should have died pretty quickly here with a very large air embolism.