CNN Talkback Live allowed viewers to comment on daily topics via fax, phone, or on-line in a chat room.
On every show a member of the audience was selected to interact with the viewers in the Talkback Live chat room. That person would later sum up on-air what was being discussed.
Susuan Rook was the original host of CNN Talkback Live however there were later on several other host including Bobbie Batista, Miles O'Brien, Daryn Kagan, Bill Hemmer, Jane Whitney, Joie Chen, Tavis Smiley, and Arthel Neville.
Talkback Live was filmed in a million dollar open air studio in the mall like atrium of CNN Global Headquarters in Atlanta.
Regular audience participant Stephen Anthony Campbell attended 362 consecutive shows before being offered a full time position with the company.