Danny has a important newscast for "Wake up San Fransisco" but Stephanie ends up getting chicken pox along with Jesse And Joey. D.J.(aka Donna Jo) gets invited to a sleepover and ends up babysitting Michelle.
Stephanie comes down with chicken pox, and as the day progresses the people who can take care of Michelle quickly dwindles. Danny may have to give up his chance to cover an important even he's been looking forward to. Meanwhile, Jesse, Joey, and Stephanie try to deal with the itching while keeping away from Michelle.—Michelle P.