Agents West and Gordon are engaged to rescue an Indian Chief's abducted daughter before the Indians retaliate. The agents learn that the miniature Dr. Miguelito Loveless, responsible for the kidnapping, has a plan to rule a land of little people, with the help of a powder he invented to reduce the size of people. During the rescue mission, Loveless shrinks Jim and the Indian Princess to a height of six inches, leaving them to defend themselves from the mad doctor's now gigantic cat.
—Anonymous