Eliot Ness and his team have been successful in shutting most of the drug trafficking in Chicago. One exception is 'Little' Charlie Sebastino's operation. He has accumulated quite a stash over the years and doesn't need to import new supplies to keep his lucrative operation going. A drug overdose victim puts Ness onto Sebastino's distribution chain but he is puzzled when the gangster stops selling the stuff. Unbeknown to Ness, the Commission, chaired by Joe Genna, has ordered Sebastino to stop selling drugs. Needless to say, 'Little' Charlie hatches his own plan to eliminate Genna and come out on top.
—garykmcd