George Costanza's (Jason Alexander) middle name is Louis, which is mentioned in this episode. It's a tribute to Lou Costello, half of the famous comedy team, Bud Abbott & Lou Costello, whose 1950s TV show was a major influence on the writing of Seinfeld.
Bob Sacamano is a fictional friend of Kramer (Michael Richards). He is never seen but is the source of many bizarre anecdotes. Larry Charles has stated that Sacamano was a real-life friend, although the two fell out shortly after the character was first introduced. Throughout the course of the series he was referenced in the following episodes:
George's breakup line "It's not you, it's me" makes its first appearance in this episode. It would later become the subject of much discussion in the season 5 episode The Lip Reader.
Seinfeld writer, Elaine Pope, became the first female writer on the show to have a script turned into a proper episode with this episode. Pope previously worked with Larry Charles, Larry David and Michael Richards on Fridays (1980).