When this episode first aired, the alien was deemed too frightening to show by several ABC affiliates. They instead showed a black screen whenever the alien appeared and showed footage of the alien later during the evening news.
This was the last episode to include the extended intro sequence.
The brief shot of Allen Leighton midway through his transition into an alien creature was devised by actor Robert Culp and makeup artist Fred B. Phillips, and was filmed without the knowledge or participation of director Byron Haskin.
When Allen has his first psychotic breakdown, he calls himself Caliban. In William Shakespeare's "The Tempest," Caliban is the son of an evil witch and what might have been a demon. He is possibly demented, certainly dangerous, and the only entity on Prospero's island not gifted with human shape.
During the opening sequence when the scientists are watching a nuclear doomsday scenario film, the scenes of terrified people running in the streets and looking up are taken from the films "It came from beneath the sea" and " The Beast from 20,000 fathoms".