Guest Star 'Ray Romano' and star Fran Drescher both attended Queens College, the main campus of which is in Flushing, Queens.
The actor who plays Maxwell really did flash the 3 actresses sitting on his bed. (Val, Fran & Sylvia Fine).
In this episode Fran Fine is attending her Hillcrest High School reunion and runs into Everybody Love's Raymond's Ray Barone (Ray Romano) In real life Fran Drescher and Ray Romano were classmates in Hillcrest High's class of 75. Both also briefly attended Queens College after graduation before dropping out with Romano eventually returning years later and making the Dean's List.
Though not really a spin off from The Nanny (1993), Ray Romano (from Everybody Loves Raymond (1996)) does show up at Fran's high school reunion establishing that they are friends and in the same fictional universe.
When Brighton is talking to Niles about C.C. being taken away and singing "Ho ho, he he, ha ha", he is referencing the song "They're Coming to Take Me Away" by Napoleon XIV.