During the episode's taping, a man in the audience had to be hospitalized after acquiring a hernia from laughing so hard.
The audience member from which Williams borrows the scarf - to improvise and create several characters from - is host James Lipton's Goddaughter. Williams didn't know at the time.
Robin Williams was on stage for four minutes before James Lipton was able to ask his first question.
The show's editors had the very daunting challenge of cutting down what ended up being several hours' worth of material from Robin Williams constantly improvising, going off on tangents and using random props between answering questions into a one-hour episode. Host James Lipton and the producers very seriously considered making this episode two hours in length, given how much footage was recorded.