Although Don Medford gets sole credit for directing this show and the next one, he only did about half of the work before getting sick and turning it over to assistant director Paul Wurtzel.
Michael Constantine and Lloyd Haines both appeared in this episode. They would appear together two years later as stars of the show (also on ABC) "Room 222".
For the famous last episode, ABC wanted to tie in the beginning of a new series that would debut after The Fugitive ended. The idea was that Clinton Judd, the lead character for the new show "Judd for the Defense" (1967) would become Richard Kimble's attorney. The problem was that the shows were being produced by different production companies and Quinn Martin was not interested in cooperating with the other show, feeling it would partially steal the spotlight from the long awaited conclusion of his series.
Fifty years later, Diane Baker would have this to say of David Janssen: "It was always a joy to work with an instinctive actor, and that's what David was."
The one-armed man is often referred to as "Fred Johnson", but he denies this is his real name, and there is no reason to believe that it is. In fact, "Fred Johnson" is merely one of several names the One-Armed Man had ID for in the episode Wife Killer (1966), and he uses several aliases throughout the series. In this episode, Gerard establishes that The One-Armed Man was known as "Gus Evans" before the murder of Helen Kimble, and that this is the name the FBI has on file for him.